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. Author manuscript; available in PMC: 2009 Oct 29.
Published in final edited form as: Nat Genet. 2008 Aug 31;40(10):1211–1215. doi: 10.1038/ng.203

Table 1.

IBD case-control association study results for GWA significant markers

Chr. SNP Position (B36) Minor allele MAF, affected MAF, control P value Bonferonni P OR 95% CI Relevant gene
1 rs11209026 67478546 A 0.024 0.061 7.47 × 10−11 3.84 × 10−5 0.385 0.29–0.52 IL23R
16 rs5743289 49314275 T 0.232 0.172 3.77 × 10−10 0.00019 1.455 1.29–1.64 NOD2
1 rs11465804 67475114 G 0.030 0.065 1.46 × 10−9 0.00075 0.442 0.34–0.58 IL23R
6 rs477515 32677669 T 0.248 0.313 1.02 × 10−8 0.0052 0.724 0.65–0.81 HLA-DRB1
6 rs2516049 32678378 G 0.248 0.313 1.06 × 10−8 0.0054 0.724 0.65–0.81 HLA-DRB1
6 rs9271568 32698441 A 0.238 0.301 2.95 × 10−8 0.015 0.724 0.65–0.81 HLA-DQA1
9 rs6478109 116608587 A 0.251 0.314 3.20 × 10−8 0.016 0.733 0.66–0.82 TNFSF15
21 rs2836878 39387404 A 0.214 0.273 6.01 × 10−8 0.031 0.725 0.65–0.81 PSMG1
20 rs2315008 61814400 T 0.250 0.311 6.30 × 10−8 0.032 0.737 0.66–0.82 TNFRSF6B
20 rs4809330 61820030 A 0.249 0.310 6.95 × 10−8 0.036 0.738 0.66–0.82 TNFRSF6B
9 rs6478108 116598524 C 0.262 0.324 8.36 × 10−8 0.043 0.743 0.67–0.83 TNFSF15
16 rs2076756 49314382 G 0.317 0.258 9.65 × 10−8 0.050 1.332 1.20–1.48 NOD2

Newly identified signals are indicated in boldface. Minor allele frequencies (MAF), P values and odds ratios (OR) are shown. The ORs shown are for the minor alleles (as observed in the controls). Combined P values are also shown, together with the most relevant gene in which the markers reside or which they are nearest to. P values are two sided and uncorrected in each instance.