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. 1964 Mar;87(3):554–561. doi: 10.1128/jb.87.3.554-561.1964

CHROMOSOMAL LOCATION OF THYMINE AND ARGININE GENES IN ESCHERICHIA COLI AND AN F′ INCORPORATING THEM

Masahide Ishibashi 1,2, Yoshinobu Sugino 1,2, Yukinori Hirota 1,2
PMCID: PMC277053  PMID: 14127570

Abstract

Ishibashi, Masahide (Osaka University, Osaka, Japan), Yoshinobu Sugino, and Yukinori Hirota. Chromosomal location of thymine and arginine genes in Escherichia coli and an F′ incorporating them. J. Bacteriol. 87:554–561. 1964.—The gene responsible for thymine requirement or independence in Escherichia coli K-12 is located on the chromosome, near Arg2 (arginine) and between Sm (streptomycin) and Ade (adenine). A new F′ (called F15) carrying the Thy (thymine) gene as well as the Arg2 gene was discovered. The Thy+ (thymine independent) gene on F15 relieves the defect of all Thy (thymine requiring) mutants of E. coli examined, such as E. coli 15 T, B3, and Thy mutants obtained by aminopterine treatment. It can also be transferred to Thy mutants of Salmonella typhimurium and Serratia marcescens, converting them to Thy+.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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