Table 4.
Frequency of mutations within RT.
| Mutations | Frequency (%) | *P value | |
|---|---|---|---|
| Group 1 | Group 2 | ||
| NNRTI | |||
| A98S/G | 26.9 | 18.9 | - |
| K101E/Q/P/R | 19.23 | 21.6 | - |
| K103N | 34.6 | 48.6 | - |
| V106M | 30.8 | 16.21 | - |
| V108I | 15.4 | 18.9 | - |
| E138A | 15.4 | 27 | - |
| V179E/D | 15.3 | 13.5 | - |
| Y181C | 23 | 27 | - |
| Y188L | 0 | 13.5 | - |
| G190A | 23 | 13.5 | - |
| NRTI (non-TAM) | |||
| K65R | 7.7 | 0 | - |
| S68G | 19.2 | 8.1 | - |
| L74V/I | 7.7 | 16.2 | - |
| Q151M | 3.8 | 2.7 | - |
| M184V | 61 | 40.5 | - |
| TAM1 | |||
| 41L | 26.9 | 40.5 | - |
| 210W | 19.2 | 18.9 | - |
| 215Y | 26.9 | 29.7 | - |
| TAM2 | |||
| 67N | 46 | 67.56 | 0.07 |
| 70R | 35 | 37.8 | - |
| 215F | 26.9 | 29.7 | - |
| 219Q | 34.6 | 37.8 | - |
| Others | |||
| E53D | 11.5 | 13.5 | - |
| K102R/Q/N | 15.4 | 0 | - |
| I135V/T | 30.8 | 45.9 | - |
| T139A/P/S | 0 | 16.2 | - |
| I142V/T | 15.4 | 8.1 | - |
| A158S | 23 | 0 | - |
| S162C/A/T | 15.4 | 24.3 | - |
| I178L/M | 19 | 35 | - |
| I202V | 34.6 | 8 | 0.008 |
| E203A/K/D | 3.8 | 18.9 | - |
| H221Y | 11.5 | 18.9 | - |
| L228R/H | 8 | 27 | 0.05 |
| D250E | 42.3 | 40.5 | - |
| K275R/Q | 23 | 8 | 0.09 |
| D324E | 27 | 8 | 0.04 |
*P value: probability of significant differences between groups