Table 1.
Characteristics | No.(%) | Characteristics | No.(%) |
---|---|---|---|
Clinical stage | Grade | ||
II B | 32 (26.9%) | I | 1 (0.8%) |
III A | 56 (47.1%) | II | 67 (56.3%) |
III B | 22 (18.5%) | III | 15 (12.6%) |
III C | 9 (7.5%) | Not graded | 36 (30.3%) |
Pre-cALN | Post-cALN | ||
negative | 36 (30.3%) | negative | 81 (68.1%) |
positive | 83 (69.7%) | positive | 38 (31.9%) |
Pre-ER | Post-ER※ | ||
negative | 58 (48.7%) | negative | 82 (75.2%) |
positive | 61 (51.3%) | positive | 27 (24.8%) |
Pre-PR | Post-PR※ | ||
negative | 60 (50.4%) | negative | 84 (77.1%) |
positive | 59 (49.6%) | positive | 25 (22.9%) |
Pre-HER-2 | Post-HER-2※ | ||
0-2+ | 86 (72.3%) | 0-2+ | 79 (72.5%) |
3+ | 33 (27.7%) | 3+ | 30 (27.5%) |
Pre-Ki67 | Post-Ki67※ | ||
≤ 20% | 74 (62.2%) | ≤ 20% | 93 (85.3%) |
>20% | 45 (37.8%) | >20% | 16 (14.7%) |
Pathology | Pathological tumor size | ||
IDC | 92 (77.3%) | ≤ 2 cm | 28 (23.5%) |
ILC | 4 (3.4%) | > 2 cm | 59 (49.6%) |
other | 23 (19.3%) | unmeasured | 32 (26.9%) |
Clinical response | pALN | ||
CR | 27 (22.7%) | N 0 | 39 (32.8%) |
PR | 78 (65.6%) | N 1-3 | 24 (20.2%) |
SD | 13 (10.9%) | N 4-9 | 35 (29.4%) |
PD | 1 (0.8%) | N >9 | 21 (17.6%) |
Pathological response in tumor site | |||
T-A | 22 (18.5%) | ||
T-B | 75 (63.0%) | ||
T-C | 22 (18.5%) |
Abbreviations: pre-, before chemotherapy; post-, after chemotherapy; cALN, clinical axillary lymph node; pALN: pathological axillary lymph node; IDC: Invasive ductal cancer; ILC: Invasive lobular cancer; CR, Complete response; PR, Partial response; SD, Stable disease; PD, Progressive disease; T-A: no tumor cell or presence of in situ carcinoma, no invasive tumor; T-B: presence of invasive carcinoma without special involvement (such as skin, vessel, more than one quadrant); T-C: presence of invasive carcinoma with special involvement.
※109 patients were evaluated after neoadjuvant chemotherapy, because of 10 patients with no residual tumor in postoperative tissue.