Table 2.
Comparison of primary categorical outcomes at baseline and follow-up between intervention and control groups while adjusting for clustering, baseline differences, and prespecified covariates*. Values are percentages (numbers) unless stated otherwise
| Variable | Valid No at baseline/follow-up | Baseline | Follow-up | Intracluster correlation coefficient | Odds ratio† (95% CI) | P value | Adjustment for multiple testing‡ | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Intervention group | Control group | Intervention group | Control group | Intervention group | Control group | |||||||
| Blood pressure: | ||||||||||||
| Systolic >140 mm Hg | 443/360 | 456/405 | 34.1 (151) | 33.8 (154) | 27.2 (98) | 32.8 (133) | 0.06 | 1.51 (0.99 to 2.30) | 0.06 | 0.18 | ||
| Diastolic >90 mm Hg | 443/360 | 458/405 | 13.3 (59) | 11.4 (52) | 8.9 (32) | 9.9 (40) | 0.29 | 1.40 (0.75 to 2.64) | 0.29 | 0.58 | ||
| Total cholesterol >5.0 mmol/l | 424/342 | 436/391 | 21.7 (92) | 22.0 (96) | 15.2 (52) | 16.4 (64) | 0.65 | 1.13 (0.63 to 2.03) | 0.65 | 0.65 | ||
| Hospital admissions§ | 433/415 | 449/435 | 24.5 (106) | 31.8 (143) | 25.8 (107) | 34.0 (148) | 0.03 | 1.56 (1.53 to 2.60) | 0.03 | 0.12 | ||
*Relevant covariates: age, sex, education, occupation, years since diagnosis, angina, myocardial infarction, coronary artery bypass grafting, percutaneous transluminal coronary angioplasty, diabetes, region, practice size. Smoking status also considered for all measurements of blood pressure.
†Intervention group compared with control group.
‡See Holm 1979.21
§Analysis of hospital admissions and practice visits carried out on adjusted end points rather than change over time, owing to different data collection intervals at baseline (12 months) and follow-up (18 months).