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. 2009 Nov 4;97(9):2399–2408. doi: 10.1016/j.bpj.2009.08.018

Figure 3.

Figure 3

Actions of CWO on the loops. (a–f) mRNA concentrations of cwo, tim, per, vri, pdp1, and CLK-CYC in response to selective activation of the repressive actions of CWO in DD conditions. Dotted black lines represent the mutant model. The red line denotes the selective activation of the CWO autorepressive loop (cwo, CWO) only. Magenta, cyan, and yellow lines indicate the activation of two repressive actions, the CWO autorepressive loop plus one of either the vri or per/tim negative loops, or the Pdp1 positive loop (pd), respectively.