Fig. 4.
%PPI in SD and LE rats for 60 min after vehicle or 0.5 mg/kg APO (s.c.). Inset shows data collapsed across 60 min; main figure shows data for 10, 30, and 120 ms prepulse intervals, across the 60-min test session. As predicted, APO markedly disrupted long interval PPI in SD (but not LE rats), and APO enhanced short interval PPI in LE (but not SD) rats. Both effects waned prior to the change in SD VP GABA efflux, as seen in Fig. 3. * Significant PPI-reducing effect of APO (all p values < 0.05); # significant PPI-enhancing effects of APO (all p values < 0.05)