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. 2009 Aug 25;37(19):6635–6643. doi: 10.1093/nar/gkp615

Table 2.

Kinetic parameters for the deamination of 5-methylcytosine and 5-methylcytosine glycol at 37°C

mdCg in nucleosidesa
Duplex DNA
mC in Duplex DNAb
(5S,6S) (5R,6R) (5S,6S) (5R,6R)
t1/2 (h) 17.1 ± 0.1 22.4 ± 0.3 37.4 ± 1.6 27.4 ± 1.0 3.3 × 108
k (h–1) (406 ± 2) × 10–4 (309 ± 4) × 10–4 (186 ± 8) × 10–4 (253 ± 10) × 10–4 2.1 × 10–9

aData from ref. (5).

bData from ref. (28).