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. 2009 Aug 27;37(19):6400–6413. doi: 10.1093/nar/gkp705

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© The Author(s) 2009. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 9. — XRCC3 acts in the same pathway as ERCC1 in ICL repair. (A) Western blot showing knockdown of ERCC1, XRCC3 or ERCC1+XRCC3 in SQ20B cells. NT, non-targeting. β-Actin was used to control for loading. (B) The effects on clonogenic survival of knocking down ERCC1, XRCC3 or ERCC1+XRCC3 in SQ20B to cisplatin treatment. NT siRNA was used as negative control. Cisplatin was added to the dishes for 2 h before changing to drug-free medium. Graph indicates average and standard deviation of three to eight experiments.