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Behavioral-state-dependent changes in glutamate concentration. Histogram of percentage change in glutamate concentration during consolidated periods of waking (all episodes >2.5 min), NREM (>3 min), or REM (>1.5 min) for all rats (n = 8). The observed changes in prefrontal and motor cortex were not significantly different from one another for any behavioral state, and thus data were pooled (n = 8). Values outside of x-axis scale (those with >2%/min) were grouped in the edge bins.
