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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Hum Genet. 2008 Oct 25;124(5):479–488. doi: 10.1007/s00439-008-0573-x

Table 2.

Regression relationships of plasma t-PA and PAI-1 with concomitants among females and males

Dependent variable Independent variable Females (n = 569)
Males (n = 423)
P value, homogeneity of regression
R2 ×100 P value R2 ×100 P value
t-PAa Age (years) 2.3 <0.001 0.7 0.078 0.326
BMI (kg/m2) 12.8 <0.001 9.0 <0.001 0.170
Systolic blood pressure 2.0 0.001 1.3 0.018 0.839
Diastolic blood pressure 2.8 <0.001 3.1 <0.001 0.939
Cholesterol 3.5 <0.001 4.4 <0.001 0.452
Glucosea 2.9 <0.001 2.7 0.001 0.631
Triglyceridesa 4.7 <0.001 2.9 <0.001 0.710
PAI-1a 7.3 <0.001 9.9 <0.001 0.276
Smoking NA NA 0.3 0.279 NA
Complete 18.4 <0.001 15.7 <0.001
PAI-1a Age (years) 1.0 0.019 0.3 0.257 0.468
BMI (kg/m2) 13.8 <0.001 13.6 <0.001 0.032
Systolic blood pressure 1.2 0.009 3.8 <0.001 0.162
Diastolic blood pressure 3.7 <0.001 5.0 <0.001 0.873
Cholesterol 3.9 <0.001 4.1 0.001 0.828
Glucosea 2.8 <0.001 4.1 <0.001 0.336
Triglyceridesa 3.4 <0.001 10.8 <0.001 0.011
t-PAa 7.3 <0.001 9.9 <0.001 0.720
Smoking NA NA 0.4 0.104 NA
Complete 19.0 <0.001 23.5 <0.001

BMI body mass index

a

Natural log transformed