Fig. 2.

Electrophysiological characterization of nifedipine-resistant current in NRVM. A: voltage dependence of activation and inactivation at early (days 2–3, n = 17) and late (days 5–7, n = 11) time in culture, in normal conditions. Values are means ± SE fitted with Boltzmann equation. B: voltage dependence of the inactivation kinetic at early and late time of culturing. Values are means ± SE. C: representative traces showing sensitivity to 50 and 250 μM NiCl₂ of the T-type current recorded at −20 mV pulse from −100 mV and the partial reversibility of NiCl₂ block (wash). Scale bars represent 25 pA and 10 ms.