Fig. 5.
Effects of H/R on voltage dependence of NiCl2-sensitive and resistant T-type currents. Voltage dependence of activation and inactivation for 50 μM Ni2+-sensitive T-type current was analyzed at early (A) and late (B) time in culture, as a tool to estimate the behavior of voltage-gated Ca2+ (Cav)3.2 in H/R conditions. Similar analysis is shown of voltage dependence of activation and inactivation for 50 μM Ni2+-resistant T-type current at early (C) and late (D) time in culture, as a tool to estimate the behavior of Cav3.1 in H/R conditions. Values are means ± SE fitted with Boltzmann equation.