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Evaluation of the ability of the model to maintain ionic stability when paced at either 1 or 2 Hz (10 min of simulation shown). The insets in A–F are the selected ion concentrations as they change during a single AP when the model is paced at either 1 or 2 Hz. A: [K+]c. B: [K+]i. C: [Ca2+]c. D: [Ca2+]i. E: [Na+]c. F: [Na+]i.
