Table 2.

Association of lower urinary tract symptoms (LUTS) with chronic illnesses by gender. Adjusted odds ratios (OR) and 95% confidence intervals (95%CI).

		Men			Women
Chronic Illnesses	AUA-SI*	N cases (weighted %)	Adjusted**OR (95%CI)		N cases (weighted %)	Adjusted OR**(95%CI)
Heart	0-7 (Mild)	147 ( 7.7)	1.00	1.00	185 (6.4)	1.00	1.00
Disease	8-19 (Moderate)	83 (19.7)	1.74 (1.03, 2.96)	1.80† (1.09, 2.96)	92 (12.2)	1.36 (0.85, 2.18)	1.57† (1.02, 2.42)
	20-35 (Severe)	18 (33.6)	2.46 (1.04, 5.81)		27 (35.4)	3.48 (1.58, 7.68)
	p-trend‡		0.011			0.007
Type 2	0-7 (Mild)	163 (6.0)	1.00	1.00	246 (6.6)	1.00	1.00
Diabetes	8-19 (Moderate)	73 (6.1)	1.92 (1.05, 3.52)	2.00† (1.12, 3.56)	97 (12.4)	1.24 (0.80, 1.92)	1.29† (0.85, 1.95)
	20-35 (Severe)	12 (25.3)	2.52 (0.73, 8.69)		19 (22.5)	1.64 (0.63, 4.31)
	p-trend‡		0.016			0.189
Hypertension	0-7 (Mild)	537 (23.1)	1.00	1.00	804 (25.6)	1.00	1.00
	8-19 (Moderate)	172 (38.7)	1.32 (0.85, 2.06)	1.30† (0.84, 2.00)	270 (37.4)	1.16 (0.81, 1.67)	1.27† (0.91, 1.77)
	20-35 (Severe)	26 (48.6)	1.16 (0.41, 3.26)		51 (65.3)	2.82 (1.39, 5.73)
	p-trend‡		0.249			0.042
Depression	0-7 (Mild)	244 (10.7)	1.00	1.00	566 (17.1)	1.00	1.00
	8-19 (Moderate)	124 (26.5)	3.26 (2.09, 5.10)	3.49† (2.29, 5.32)	211 (30.4)	1.92 (1.36, 2.71)	2.11† (1.53, 2.90)
	20-35 (Severe)	23 (50.3)	7.41 (2.54, 21.64)		53 (59.5)	4.52 (2.31, 8.86)
	p-trend‡		<0.001			<0.001

^*American Urological Association Symptom Index

^**Adjusted for age, race/ethnicity, BMI, physical activity, smoking alcohol consumption, comorbid conditions

^†OR for the 8-19 and 20-35 categories combined compared to the 0-7 category

^‡p-value for trend across the 3 AUA-SI categories