Table 5.
Association of the metabolic syndrome and LUTS stratified by age. Adjusted* odds ratios and 95% confidence intervals. Bold indicates a statistical significance.
| Age<60 (N=1502), Adjusted* OR (95%CI) |
Age≥60 (N=397), Adjusted* OR (95%CI) |
||||
|---|---|---|---|---|---|
| AUA-SI | 0-1 | 1.00 | 1.00 | 1.00 | 1.00 |
| 2-7 | 1.92 (1.29, 2.86) |
1.99† (1.39, 2.86) |
1.14 (0.55, 2.38) | 1.04† (0.51, 2.10) |
|
| |
≥8 |
2.21 (1.28, 3.82) |
0.92 (0.40, 2.13) |
||
| Voiding score | <5 | 1.00 | 1.00 | ||
| |
≥5 |
1.86 (0.96, 3.58) |
|
1.73 (0.87, 3.44) |
|
| Storage score | <4 | 1.00 | 1.00 | ||
| |
≥4 |
1.15 (0.75, 1.77) |
|
0.87 (0.44, 1.71) |
|
| Bother score | Continuous | 1.09 (1.01, 1.12) | 1.02 (0.98, 1.07) | ||
| 0 | 1.00 | 1.00 | |||
| 1-8 | 0.89 (0.50, 1.61) | 0.86 (0.43, 1.71) | |||
| |
≥9 |
5.04 (1.48, 17.09) |
|
1.56 (0.72, 3.51) |
|
| Incomplete Emptying** | None | 1.00 | 1.00 | 1.00 | 1.00 |
| Mild | 2.16 (1.35, 3.46) |
2.01† (1.26, 3.20) |
0.98 (0.50, 1.91) | 0.92† (0.49, 1.71) |
|
| |
Severe |
1.48 (0.38, 5.78) |
0.68 (0.22, 2.14) |
||
| Intermittency** | None | 1.00 | 1.00 | 1.00 | 1.00 |
| Mild | 2.14 (1.20, 3.79) |
1.98† (1.22, 3.20) |
0.89 (0.45, 1.77) | 0.98† (0.53, 1.84) |
|
| |
Severe |
1.54 (0.70, 3.36) |
1.25 (0.43, 3.66) |
||
| Weak Stream** | None | 1.00 | 1.00 | 1.00 | 1.00 |
| Mild | 1.45 (0.85, 2.48) | 1.28† (0.79, 2.08) |
1.22 (0.61, 2.44) | 1.03† (0.54, 1.95) |
|
| |
Severe |
0.88 (0.35, 2.24) |
0.73 (0.28, 1.91) |
||
| Straining** | None | 1.00 | 1.00 | 1.00 | 1.00 |
| Mild | 1.53 (0.75, 3.13) | 1.65† (0.84, 3.23) |
0.94 (0.38, 2.33) | 1.02† (0.45, 2.33) |
|
| |
Severe |
2.02 (0.41, 9.98) |
1.63 (0.41, 6.54) |
||
| Frequency** | None | 1.00 | 1.00 | 1.00 | 1.00 |
| Mild | 1.01 (0.66, 1.55) | 0.94† (0.63, 1.41) |
0.74 (0.38, 1.42) | 0.68† (0.37, 1.24) |
|
| |
Severe |
0.81 (0.43, 1.55) |
0.61 (0.26, 1.45) |
||
| Urgency** | None | 1.00 | 1.00 | 1.00 | 1.00 |
| Mild | 1.40 (0.70, 2.78) | 1.52† (0.85, 2.70) |
1.27 (0.62, 2.61) | 1.53† (0.85, 2.77) |
|
| |
Severe |
2.04 (0.90, 4.64) |
2.14 (0.96, 4.74) |
||
| Nocturia*** | 0 | 1.00 | 1.00 | 1.00 | 1.00 |
| 1 | 2.15 (1.34, 3.43) | 2.24† (1.48, 3.39) | 0.68 (0.33, 1.39) | 0.80† (0.43, 1.50) | |
| ≥2 | 2.43 (1.46, 4.03) | 0.93 (0.46, 1.88) | |||
*
Adjusted for race/ethnicity, SES, physical activity, alcohol consumption, pack-years of smoking, LUTS medications
**
Symptoms categorized as: None (I do not have the symptom) Mild (rarely/a few times) Severe (fairly often/usually/almost always)
***
Number of times have to go to the bathroom at night after falling asleep
†
OR for AUA-SI categories 2-7 and ≥8 combined, or categories mild and severe combined