Figure 4.

(a) Cardiovascular anatomy in mice with a deletion of the Idd–Arvcf interval. A section of the adult heart from a mouse with a deletion of the Idd–Arvcf interval shows the normal anatomy of the atrioventricular region. a, Right atrium; b, atrial septum; c, left atrium; d, mitral valve; e, ventricular septum; f, ventricular free wall; g, tricuspid valve. (b) Corrosion cast of a heart, major branches from the aortic arch, and pulmonary artery in an E18.5 embryo with a deletion of the Idd–Arvcf interval, showing normal development of the major vessels. H, heart; Ao, aorta; IA, innominate artery; LCC and RCC, left and right common carotid arteries; LSA and RSA, left and right subclavian arteries; PA, pulmonary artery.