Table 4.
Patterns of gene expression in gingival tissues, according to subgingival levels of A. actinomycetemcomitans, P. gingivalis, T. forsythia and T. denticola.
| A. actinomycetemcomitans | P. gingivalis | T. forsythia | T. denticola | |
|---|---|---|---|---|
| 1 | antigen processing and presentation | 1 | 1 | 1 |
| 2 | apoptotic mitochondrial changes | 96 | 101 | 96 |
| 3 | antigen processing and presentation of peptide antigen | 3 | 3 | 3 |
| 4 | antigen processing and presentation of peptide antigen via MHC class I | 4 | 3 | 5 |
| 5 | phosphate transport | 56 | 63 | 71 |
| 6 | muscle development | 38 | 39 | 44 |
| 7 | MAPKKK cascade | 5 | 4 | 7 |
| 8 | protein-chromophore linkage | 152 | 150 | 147 |
| 9 | hemopoietic or lymphoid organ development | 9 | 11 | 10 |
| 10 | hemopoiesis | 11 | 12 | 11 |
| 11 | immune system development | 8 | 10 | 9 |
| 12 | protein amino acid N-linked glycosylation | 50 | 81 | 52 |
| 13 | fatty acid biosynthetic process | 17 | 21 | 8 |
| 14 | regulation of anatomical structure morphogenesis | 7 | 6 | 7 |
| 15 | acute inflammatory response | 24 | 18 | 21 |
| 16 | humoral immune response | 37 | 40 | 35 |
| 17 | activation of immune response | 62 | 58 | 54 |
| 18 | regulation of cell adhesion | 51 | 45 | 47 |
| 19 | regulation of cell differentiation | 2 | 2 | 2 |
| 20 | hemostasis | 12 | 15 | 14 |
The left column lists the top 20 differentially expressed Gene Ontology (GO) groups, according to levels of A. actinomycetemcomitans while columns to the right describe the ranking of these particular GO groups for the other three species.