Table 4.

Effect of APAP on Hemodynamic and Neurohumoral Measures

	Control Group		Treatment Group		Change From Baseline
Parameters	Baseline	Final	Baseline	Final	Control Group	Treatment Group	p Value
24-h urinary norepinephrine, μg/24 h	0.041	0.038	0.034	0.023	− 0.003	− 0.011	− 0.0008
							(0.18)
BNP level, pg/mL	1,223	1,240	1,121	664	17	− 457	− 474
							(0.13)
BUN level, mg/dL	24.9	22.5	28.7	30.3	− 2.4	1.6	4.1
							(0.18)
Creatinine level, mg/dL	1.30	1.27	1.36	1.57	− 0.03	0.21	− 0.24
							(0.19)
Systolic BP, mm Hg	110	105	107	100	− 5.2	− 6.5	− 1.3
							(0.78)
Diastolic BP, mm Hg	66	65	66	63	− 1.2	− 3	− 1.9
							(0.6)
Weight, kg	97	96	102	100	− 0.5	− 2	− 1.5
							(0.048)