Table 2.
Surgeries for abnormalities in endometrial surveillance
| Patient (no) | Age | Indication endometrial sampling | Mutation | Endometrial thickness (ET) (TVU) | Method | Surgery | Pathology |
|---|---|---|---|---|---|---|---|
| 1 | 45 | Routine | MSH6 | 4 | Microcurettage → endometrial carcinoma | → BSO and hysterectomy | Complex hyperplasia with atypia |
| 2 | 55 | ET > 4 mm at TVU | MLH1 | 8 | Microcurettage → complex hyperplasia with atypical signs | → BSO and hysterectomy | Moderately differentiated endometroid adenocarcinoma; stage IC |
| 3 | 52 | Irregular bleedings at first visit (prevalent case) | MSH2 | Endometrium not visible | Curettage → poorly differentiated endometroid adenocarcinoma | → BSO and hysterectomy | Moderate adenocarcinoma; stage IIIC |
| 4 | 46 | Routine | MLH1 | 3.5 | Microcurettage → complex hyperplasia with atypia | → BSO and hysterectomy | Complex hyperplasia with atypia |
| 5 | 48 | ET > 4 mm at TVU | MLH1 | 4.8 | Microcurettage (failed) hysteroscopy with biopsy → complex hyperplasia with atypia | → BSO with hysterectomy | Simple hyperplasia with atypia |
| 6 | 56 | Routine | MLH1 | Unknown | Microcurettage → complex hyperplasia with atypia | → Hysterectomy (BSO in history because of cyst) | Complex hyperplasia with atypia |
| 7 | 51 | Routine | MSH6 | 4 | Microcurettage (failed) hysteroscopy with biopsy → complex hyperplasia with atypia | → BSO with hysterectomy | Moderately differentiated endometroid adenocarcinoma; stage 1B1 |
ET endometrial thickness; (B)SO (bilateral) salpingo-oophorectomy; TVU transvaginal ultrasound