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. 2009 Jun 6;8(4):391–397. doi: 10.1007/s10689-009-9252-x

Table 4.

Results of surveillance tools and interventions

Surveillance tool or diagnostic intervention Number of patients Outcome
TVU 285 240 Normal
23 Ovarian abnormality → cyst

12 additional consults → 8 surgeries:

1 → ovarian carcinoma a

1 → mature teratoma

1 → borderline malignancy

5 → normal ovaries

22

Endometrial abnormality

12 → endometrial thickness increased

5 → polyp

5 → myoma

→ Microcurettage/hysteroscopy with biopsy or curettage
CA 125 (U/ml) 270 265 ≤35
5 >35

→ 316 → also enlarged ovary → ovarian carcinoma a

→ 162,6 → also enlarged ovary → exploration: borderline malignancy

→ 81 → repeat of measurement: same outcome → exploration → normal anatomy

→ 42,4 → exploration → normal anatomy

→ 51,0 → exploration → normal anatomy

Microcurettage/curettage/biopsy taken as routine (after January 2006) 64 49 Normal
11 Inadequate material Further analysis as possibleb
4 Abnormal

3  hyperplasia with atypia

1  endometrial carcinoma

Microcurettage/curettage/biopsy taken after complaints or abnormal TVU (before Jan 2006) 32 24 Normal
5 Inadequate material Further analysis as possibleb
3 Abnormal

1  hyperplasia with atypia

2  endometrial carcinoma

aSame patient with ovarian cancer: enlarged ovary and elevated CA 125

bReturn to surveillance for in total two patients without final pathological diagnosis, but low clinical suspicion