Table 4.
Surveillance tool or diagnostic intervention | Number of patients | Outcome | ||
---|---|---|---|---|
TVU | 285 | 240 | Normal | |
23 | Ovarian abnormality → cyst |
12 additional consults → 8 surgeries: 1 → ovarian carcinoma a 1 → mature teratoma 1 → borderline malignancy 5 → normal ovaries |
||
22 |
Endometrial abnormality 12 → endometrial thickness increased 5 → polyp 5 → myoma |
→ Microcurettage/hysteroscopy with biopsy or curettage | ||
CA 125 (U/ml) | 270 | 265 | ≤35 | |
5 | >35 |
→ 316 → also enlarged ovary → ovarian carcinoma a → 162,6 → also enlarged ovary → exploration: borderline malignancy → 81 → repeat of measurement: same outcome → exploration → normal anatomy → 42,4 → exploration → normal anatomy → 51,0 → exploration → normal anatomy |
||
Microcurettage/curettage/biopsy taken as routine (after January 2006) | 64 | 49 | Normal | |
11 | Inadequate material | Further analysis as possibleb | ||
4 | Abnormal |
3 → hyperplasia with atypia 1 → endometrial carcinoma |
||
Microcurettage/curettage/biopsy taken after complaints or abnormal TVU (before Jan 2006) | 32 | 24 | Normal | |
5 | Inadequate material | Further analysis as possibleb | ||
3 | Abnormal |
1 → hyperplasia with atypia 2 → endometrial carcinoma |
aSame patient with ovarian cancer: enlarged ovary and elevated CA 125
bReturn to surveillance for in total two patients without final pathological diagnosis, but low clinical suspicion