. Author manuscript; available in PMC: 2009 Nov 2.

Published in final edited form as: Eur J Pain. 2007 Jul 30;12(3):293–300. doi: 10.1016/j.ejpain.2007.06.001

Table 1. ET-1 and ETAR mRNA Expression Levels in the Paw Cancers and Associated Cell Lines. ET-1 Concentration in Paw Cancers and Conditioned Medium.

Cancer Type	ET-1 mRNA expression level	ETAR mRNA expression level	ET-1 level in tissue or cell culture medium (pg/ml)
SCC	257.8 ± 72.1^*	13.00 ± 3.01^*	63.5 ± 21.9^*
Melanoma	0.1 ± 0.1	0.06 ± 0.02	6.6 ± 2.9
Cell Line
HSC-3 (SCC)	1110.5^†	16.3^†	34.02
WM164 (melanoma)	1.22	0.29	Not detectable

significantly more in SCC relative to melanoma

^†

significantly more in HSC-3 relative to WM164