Table 1.
Plasma phospholipid FA profile in healthy subjects and in patients with obstructive jaundice before and after the n-3 FA supplementation.
Fatty acid | Control group | Patients, baseline | Patients, after supplementation |
---|---|---|---|
16:00 | 23.77 ± 1.13 | 31.6 ± 2.84*** | 32.46 ± 2.40 |
16:1 n-7 | 0.24 ± 0.09 | 1.08 ± 0.32*** | 1.23 ± 0.37 |
18:00 | 14.88 ± 1.18 | 13.66 ± 2.09 | 13.58 ± 2.74 |
18:1 n-9 | 11.85 ± 1.69 | 14.31 ± 2.19** | 14.77 ± 1.14 |
18:2 n-6 | 28.39 ± 2.81 | 24.84 ± 3.43* | 22.87 ± 2.03 |
20:3 n-6 | 2.71 ± 0.84 | 2.59 ± 1.01 | 2.39 ± 0.65 |
20:4 n-6 | 12.41 ± 2.20 | 8.81 ± 1.50*** | 8.75 ± 1.43 |
20:5 n-3 | 0.41 ± 0.24 | 0.18 ± 0.07** | 0.55 ± 0.24### |
22:4 n-6 | 0.86 ± 0.38 | 0.35 ± 0.13*** | 0.36 ± 0.12 |
22:5 n-3 | 0.71 ± 0.16 | 0.35 ± 0.1*** | 0.50 ± 0.16# |
22:6 n-3 | 3.84 ± 1.06 | 2.22 ± 0.74*** | 2.53 ± 0.71 |
SFA | 38.64 ± 2.12 | 45.26 ± 2.73*** | 46.04 ± 2.29 |
MUFA | 12.09 ± 1.68 | 15.39 ± 2.41*** | 16.0 ± 1.27 |
PUFA | 49.22 ± 1.92 | 39.34 ± 3.38*** | 37.95 ± 2.65 |
n-6 | 44.27 ± 1.80 | 36.59 ± 3.24*** | 34.38 ± 2.38 |
n-3 | 4.96 ± 1.28 | 2.75 ± 0.78*** | 3.58 ± 0.9# |
n-6/n-3 | 9.47 ± 2.39 | 14.24 ± 3.55** | 10.24 ± 2.78# |
All data are presented as a mean ± SE. Fatty acids concentrations are expressed in % of totally detected FA. SFA-saturated fatty acids. MUFA-monounsaturated fatty acids. PUFA- polyunsaturated fatty acids. **p<0.01, ***p<0.001-between control group and patients before treatment. #p<0.05, ###p<0.001 intergroups compared baseline to after 7 day supplementation.