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. 2009 Nov 11;4(11):e7593. doi: 10.1371/journal.pone.0007593

Figure 4. Screening of C. elegans mutants in search of nematicidal targets of HWY-4213.

Figure 4

Total 39 C. elegans mutants that are known to be deficient in channel proteins were tested for their resistance to HWY-4213 using the HTS method. Five mutant strains that are associated with either calcium channel or muscle genes are shown to be resistant to HWY-4213.