Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Nov 11;4(11):e7593. doi: 10.1371/journal.pone.0007593

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Oh et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Based on the primary screening results, we hypothesized that HWY-4213 kills the nematode B. xylophilus by inhibiting functions of certain calcium channel proteins as well as the UNC-9 protein in gap junctions, which could result in bursting of calcium ions. The exact mechanism of action involving this calcium channel blocking by HWY-4213 remains to be established.