Table 5. Relative sensitivity of B. xylophilus to Ca2+ channel blockers.
Test compounds | Ca+ channel type | Lethality against B. xylophilus (%)* | ||
0.01 mM | 0.1 mM | 1 mM | ||
HWY-4213 | - | 0.0 | 21.1 (±2.5) | 100.0 |
Amlodipine | L | 0.0 | 0.0 | 0.0 |
Bepridil | L | 0.0 | 0.0 | 9.8 (±2.4) |
Diltiazem | L | 0.0 | 0.0 | 2.5 (±1.2) |
Felodipine | L | 0.0 | 0.0 | 10.1 (±3.2) |
Isradipine | L | 0.0 | 0.0 | 5.6 (±2.6) |
Nicardipine | L | 0.0 | 0.0 | 0.0 |
Nifedipine | L | 0.0 | 0.0 | 0.0 |
Nimodipine | L | 0.0 | 0.0 | 0.0 |
Verapamil | L | 0.0 | 0.0 | 24.3 (±5.1) |
Mibefradil | T | 0.0 | 0.0 | 36.8 (±5.7) |
*Values are mean±SD (n = 3).