Table 4.

Genotype and allele frequency distributions

		European-Americans				African-Americans
		Cases (n=235)		Controls (n=298)		Cases (n=82)		Controls (n=48)
		n	f	n	f	n	f	n	f
P1328	TT	29	0.148	30	0.102	8	0.136	4	0.087
	TC	84	0.429	135	0.458	11	0.186H1	11	0.239
	CC	83	0.423	130	0.441	40	0.678	31	0.674
	T	142	0.362δ1	195	0.331	27	0.229	19	0.207
	C	250	0.638	395	0.669	91	0.771	73	0.793
P1333	TT	29	0.188	62	0.213	5	0.125	6	0.128
	TC	82	0.532J1	140	0.481	16	0.400	10	0.213H4
	CC	43	0.279	89	0.306	19	0.475	31	0.660
	T	140	0.455	264	0.454	26	0.325δ2	22	0.234
	C	168	0.545	318	0.546	54	0.675	72	0.766
P1655	CC	31	0.197	58	0.197	4	0.093	6	0.125
	CG	78	0.497	140	0.475	19	0.442	11	0.229H5
	GG	48	0.306	97	0.329	20	0.465	31	0.646
	C	140	0.446	256	0.434	27	0.314	23	0.240
	G	174	0.554	334	0.566	59	0.686	73	0.760
P1320	TT	12	0.069	22	0.075	12	0.255	10	0.213
	TC	55	0.314	80	0.274H2	18	0.383J2	21	0.447
	CC	108	0.617	190	0.651	17	0.362	16	0.340
	T	79	0.226	124	0.212	42	0.447	41	0.436
	C	271	0.774	460	0.788	52	0.553	53	0.564
P1578	TT	0	0.000	5	0.017	7	0.092	3	0.063
	TC	44	0.201A1	38	0.131H3	35	0.461	25	0.521
	CC	175	0.799	247	0.852	34	0.447	20	0.417
	T	44	0.100	48	0.083	49	0.322	31	0.323
	C	394	0.900	532	0.917	103	0.678	65	0.677
P1583	AA	27	0.130	36	0.125	2	0.027	3	0.063
	AG	92	0.442	128	0.443	32	0.427A2	11	0.229
	GG	89	0.428	125	0.433	41	0.547	34	0.708
	A	146	0.351	200	0.346	36	0.240	17	0.177
	G	270	0.649	378	0.654	114	0.760	79	0.823

n, individual number (for genotypes) or chromosome number (for alleles); f, frequency; p<0.05 for ^ACase-control frequency comparison and ^HHardy-Weinberg Disequilibrium test;

^δThe marker with highest δ among all markers (δ₁=0.047 for P1328 in EAs; δ₂=0.119 for P1333 in AAs);

^JThe marker with highest J value among all markers (J₁=0.062 for P1333 in EAs; J₂=0.182 for P1320 in AAs).