Table 5.
Handling and Acceptance Questionnaire (Selected Questions)
| Patients (n) | 32 | 29 | 61 |
|---|---|---|---|
| Intuitiveness Group n (%) | Instruction Time Group n (%) | Total n (%) | |
| HAQ Question 11: Which pen has the highest quality? | |||
| Equal | 12 (37.5) | 4 (13.8) | 16 (26.2) |
| FlexPen | 4 (12.5) | 12 (41.4) | 16 (26.2) |
| OptiClik | 16 (50.0) | 13 (44.8) | 29 (47.5) |
| Difference % (FlexPen–OptiClik) | −37.5 | −3.4 | −21.3 |
| 95% CI for difference % | (−61.6,−13.4) | (−37.2, 30.3) | (−42.2, −0.4) |
| p value | .0023 | .8414 | .0454 |
| HAQ Question 13: Which pen is the most convenient? | |||
| Equal | 6 (18.8) | 4 (13.8) | 10 (16.4) |
| FlexPen | 21 (65.6) | 22 (75.9) | 43 (70.5) |
| OptiClik | 5 (15.6) | 2 (6.9) | 7 (11.5) |
| Difference % (FlexPen–OptiClik) | 50 | 69 | 59 |
| 95% CI for difference % | (24.0, 76.0) | (47.4, 90.6) | (41.8, 76.2) |
| p value | .0002 | < .0001 | < .0001 |
| HAQ Question 16: Which pen is the simplest to use? | |||
| Equal | 4 (12.5) | 3 (10.3) | 7 (11.5) |
| FlexPen | 23 (71.9) | 24 (82.8) | 47 (77.0) |
| OptiClik | 5 (15.6) | 2 (6.9) | 7 (11.5) |
| Difference % (FlexPen–OptiClik) | 56.3 | 75.9 | 65.6 |
| 95% CI for difference % | (30.4, 82.1) | (55.2, 96.5) | (48.6, 82.5) |
| p value | < .0001 | < .0001 | < .0001 |
| HAQ Question 19: With which pen is it easiest to inject the dose? | |||
| Equal | 5 (15.6) | 7 (24.1) | 12 (19.7) |
| FlexPen | 21 (65.6) | 20 (69.0) | 41 (67.2) |
| OptiClik | 6 (18.8) | 2 (6.9) | 8 (13.1) |
| Difference % (FlexPen–OptiClik) | 46.9 | 62.1 | 54.1 |
| 95% CI for difference % | (19.5, 74.2) | (39.8, 84.3) | (36.2, 72.0) |
| p value | .0008 | < .0001 | < .0001 |
| HAQ Question 24: With which pen do you feel most confident that the full dose has been injected? | |||
| Equal | 13 (40.6) | 4 (13.8) | 17 (27.9) |
| FlexPen | 17 (53.1) | 20 (69.0) | 37 (60.7) |
| OptiClik | 2 (6.3) | 5 (17.2) | 7 (11.5) |
| Difference % (FlexPen–OptiClik) | 46.9 | 51.7 | 49.2 |
| 95% CI for difference % | (25.7, 68.1) | (23.7, 79.8) | (31.8, 66.6) |
| p value | < .0001 | .0003 | < .0001 |
| HAQ Question 25: Which pen do you feel is the safest to operate? | |||
| Equal | 18 (56.3) | 12 (41.4) | 30 (49.2) |
| FlexPen | 9 (28.1) | 13 (44.8) | 22 (36.1) |
| OptiClik | 5 (15.6) | 4 (13.8) | 9 (14.8) |
| Difference % (FlexPen–OptiClik) | 12.5 | 31 | 21.3 |
| 95% CI for difference % | (−10.0, 35.0) | (5.6, 56.5) | (4.2, 38.4) |
| p value | .2763 | .0170 | .0144 |
| HAQ Question 31: Which pen would you trust the most for delivering your insulin injections? | |||
| Equal | 17 (53.1) | 11 (37.9) | 28 (45.9) |
| FlexPen | 9 (28.1) | 15 (51.7) | 24 (39.3) |
| OptiClik | 6 (18.8) | 3 (10.3) | 9 (14.8) |
| Difference % (FlexPen–OptiClik) | 9.4 | 41.4 | 24.6 |
| 95% CI for difference % | (−14.1, 32.9) | (17.0, 65.8) | (7.2, 42.0) |
| p value | .4342 | .0009 | .0056 |
| HAQ Question 34: Overall, which pen was the most simple to use? | |||
| Equal | 2 (6.3) | 2 (6.9) | 4 (6.6) |
| FlexPen | 25 (78.1) | 25 (86.2) | 50 (82.0) |
| OptiClik | 5 (15.6) | 2 (6.9) | 7 (11.5) |
| Difference % (FlexPen–OptiClik) | 62.5 | 79.3 | 70.5 |
| 95% CI for difference % | (36.9, 88.1) | (59.3, 99.3) | (53.9, 87.1) |
| p value | < .0001 | < .0001 | < .0001 |
| HAQ Question 35: Overall, which pen would you prefer to use every day (if necessary)? | |||
| Equal | 2 (6.3) | 1 (3.4) | 3 (4.9) |
| FlexPen | 26 (81.3) | 24 (82.8) | 50 (82.0) |
| OptiClik | 4 (12.5) | 4 (13.8) | 8 (13.1) |
| Difference % (FlexPen–OptiClik) | 68.8 | 69 | 68.9 |
| 95% CI for difference % | (45.1, 92.4) | (43.5, 94.4) | (51.5, 86.2) |
| p value | < .0001 | < .0001 | < .0001 |