Table 2.
Comparison of Photobleaching Tendency of Common Organic and Nanoparticle Fluorophoresa
Fluorescent probe | Photobleaching rate constant (h-1) | Fluence (mW/cm2) | Nominal sensor lifetime |
---|---|---|---|
IR-Dye 78-CA32 | 250.92 | 600 | 3.2 s |
Cy532 | 20.52 | 600 | 39.1 s |
Indocyanine Green31 | 0.0412 | 28 | 5.4 h |
Type II NIR QD32 | 0.0827 | 600 | 2.7 h |
SWNT33 | 0 | 1.0 × 106 | α |
Estimated optical sensor device lifetime is calculated from Equation (2).