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. Author manuscript; available in PMC: 2009 Nov 2.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2008 Jun 12;28(9):1627–1633. doi: 10.1161/ATVBAHA.108.168278

Fig. 4. Acute exposure of extracellular SOD reveals eNOS activation in blood vessels expressing Nox5.

Fig. 4

Aortic endothelium was transduced with control or Nox5 adenovirus (6×1011particles/ml). 36hrs later, aortic rings were precontracted with PE and acutely exposed to 100U/ml SOD and the degree of relaxation recorded. Representative traces of the changes in isometric tension are shown in A-B. In C, data is summarized as the percentage of PE-induced tone in response to SOD in control and Nox5 transduced blood vessels. *P<0.05 vs the control (n=5).