TABLE 1.
Summary of Clinical Data of Patients With RP10 Autosomal-Dominant Retinitis Pigmentosa
| Subject | RFSW | Age, yr | Sex | VA OD | VA OS | Color Vision | Onset of Night Blindness | VF Total Sensitivity (dB) | VF Diameter (Degrees) |
DA Elevation (Log Units) | Additional Ophthalmologic Findings |
|---|---|---|---|---|---|---|---|---|---|---|---|
| IV/5 | 6890 | 60 | F | LP | 20/63 | Tritan | Late 20s | 0 | 0 | 3.34 | Glaucoma |
| V/11 | 6879 | 51 | M | 20/63 | 20/80 | Tritan | Childhood | 106 | 15 | 1.97 | CME OD |
| V/10 | 6885 | 49 | F | 20/25 | 20/25 | Normal | Early childhood | 39 | 10 | 3.14 | |
| V/14 | 6880 | 43 | F | 20/80 | 20/80 | Normal | Childhood | 148 | 20 | 1.65 | CME OU |
| VI/1 | 6889 | 26 | M | 20/32 | 20/32 | Normal | Childhood | 717 | 30 | 0.56 | |
| VI/2 | 6888 | 22 | M | 20/25 | 20/25 | Normal | Childhood | 1441 | 55 | 0.37 | |
| VI/9 | 6877 | 20 | M | 20/63 | 20/125 | Normal | Early childhood | 174 | 20 | 1.61 | CME OD, amblyopia |
| OS | |||||||||||
| VI/4 | 6883 | 19 | F | 20/32 | 20/32 | Normal | Early childhood | 398 | 30 | 1.24 | Coat disease |
| VI/5 | 6887 | 16 | F | 20/32 | 20/40 | Normal | Early childhood | 1429 | 60 | 0.41 | |
| VI/6 | 6886 | 13 | M | 20/32 | 20/32 | Normal | Early childhood | 589 | 20 | 2.66 | |
| VI/25 | 6881 | 13 | M | 20/100 | 20/100 | Nonspecific | Childhood | 1023 | 45 | 0.00 | CME OU |
| Unaffected | |||||||||||
| VI/3 | 6884 | 24 | F | 20/13 | 20/13 | Normal | NA | 2159 | >120 | 0.00 | |
| VI/10 | 6878 | 16 | F | 20/25 | 20/25 | Normal | NA | 2104 | >120 | 0.00 |
DA = dark-adapted threshold; LP = light perception; NA = not applicable; OD = right eye; OS = left eye; OU = both eyes; RFSW = Retina Foundation of the Southwest; VA = visual acuity; VF = visual field.