Table 1.
Characteristics of 984 Participants, Divided by the Presence of Depression
| Variables | Current Depression n = 217 |
No Current Depression n = 767 |
p Value |
|---|---|---|---|
| Demographic: | |||
| Age (years) | 62 ± 11 | 68 ± 11 | < .0001 |
| Male | 149 (69%) | 652 (85%) | < .0001 |
| White | 131 (60%) | 464 (61%) | .96 |
| Medical history: | |||
| Myocardial infarction | 107 (50%) | 420 (55%) | .17 |
| Congestive heart failure | 40 (19%) | 133 (17%) | .71 |
| Diabetes mellitus | 68 (31%) | 192 (25%) | .07 |
| Medication use: | |||
| Statin | 126 (58%) | 506 (66%) | .03 |
| Beta blocker | 119 (55%) | 446 (58%) | .38 |
| Hormone replacement therapy | 14 (6%) | 32 (4%) | .16 |
| Aspirin | 168 (77%) | 593 (77%) | .97 |
| Antidepressant | 102 (47%) | 79 (10%) | < .0001 |
| Other characteristics: | |||
| Regular alcohol use | 66 (31%) | 219 (29%) | .61 |
| Current smoking | 63 (29%) | 132 (17%) | .0001 |
| Body Mass Index (kg/m2) | 29 ± 5.6 | 28 ± 5.3 | .06 |
| Physically active | 114 (53%) | 508 (66%) | .0002 |
| Creatinine clearance (mL/min) | 87.4 ± 30.2 | 79.4 ± 28 | .0009 |
| Cardiac function: | |||
| Resting left ventricular ejection fraction | .63 ± .08 | .61 ± .10 | .009 |
| Systolic blood pressure (mm Hg) | 133 ± 22 | 133 ± 21 | .96 |
| Diastolic blood pressure (mm Hg) | 75 ± 12 | 74 ± 11 | .26 |
| Low-density lipoprotein (mg/dL) | 107 ± 37 | 104 ± 33 | .24 |
| High-density lipoprotein (mg/dL) | 45 ± 15 | 46 ± 14 | .79 |
| Inducible ischemia | 35 (18%) | 182 (26%) | .04 |