Table. 4.
Univariable and Multivariable Cox Regression Analyses for Time-to-Allograft-Loss in Patients with Lupus Nephritis who had Undergone Kidney Transplantation
| Variable | Hazard ratio |
Univariable 95% Confidence interval |
p value | Hazard ratio |
Multivariable 95% Confidence interval |
p value |
|---|---|---|---|---|---|---|
| Age | 0.98 | 0.96–1.01 | 0.1495 | 1.00 | 0.97 – 1.04 | 0.8067 |
| Gender (male) | 0.89 | 0.46–1.69 | 0.7128 | 0.96 | 0.40 – 2.27 | 0.9228 |
| Ethnicity (African American) | 2.24 | 1.28–3.93 | 0.0050 | 2.71 | 1.35 – 5.44 | 0.0049 |
| Smoker | 1.24 | 0.69–2.22 | 0.4663 | 2.04 | 0.98 – 4.25 | 0.0575 |
| Recurrent lupus nephritis | 1.52 | 0.75–3.10 | 0.2418 | 1.76 | 0.78 – 4.00 | 0.1756 |
| Living-related donor* | 0.79 | 0.46–1.35 | 0.3804 | |||
| Living-unrelated donor* | 0.53 | 0.13–2.18 | 0.3785 | |||
| Post-transplant medications | ||||||
| Azathioprine | 1.52 | 0.88–2.62 | 0.1345 | |||
| Cyclosporine A | 1.64 | 0.77–3.49 | 0.1986 | |||
| Mycophenolate mofetil | 0.60 | 0.36–1.02 | 0.0552 | 0.59 | 0.32 – 1.07 | 0.0814 |
| Tacrolimus | 1.35 | 0.77–2.35 | 0.2918 | |||
*
Deceased donor is the reference group.