Table. 5.
Univariable and Multivariable Cox Regression Analyses for Time-to-Allograft-Loss in Patients with Lupus Nephritis who had Undergone Kidney Transplantation*
Variable | Hazard ratio |
Univariable 95% Confidence interval |
p value | Hazard ratio |
Multivariable 95% Confidence interval |
p value |
---|---|---|---|---|---|---|
Age | 0.98 | 0.95 – 1.02 | 0.3030 | 1.00 | 0.96 – 1.04 | 0.9556 |
Gender (male) | 1.29 | 0.59 – 2.85 | 0.5185 | 1.75 | 0.69 – 4.42 | 0.2402 |
Ethnicity (African American) | 2.48 | 1.19 – 6.28 | 0.0172 | 3.14 | 1.21 – 8.14 | 0.0187 |
Smoker | 1.63 | 0.76 – 3.52 | 0.2135 | |||
Living-related transplant † | 0.57 | 0.26 – 1.27 | 0.1706 | |||
Living-unrelated transplant† | 0.45 | 0.06 – 0.31 | 0.4304 | |||
Recurrent lupus nephritis | 0.58 | 0.14 – 2.45 | 0.4610 | 0.58 | 0.14 –2.50 | 0.4646 |
Azathioprine | 2.41 | 1.10 – 5.27 | 0.0277 | 1.20 | 0.47 – 3.06 | 0.7014 |
Cyclosporine | 1.94 | 0.67 – 5.62 | 0.2210 | |||
Mycophenolate | 0.29 | 0.14 – 0.58 | 0.0005 | 0.55 | 0.24– 1.26 | 0.1566 |
Tacrolimus | 0.68 | 0.29 – 1.59 | 0.3730 |
Estimates for allograft loss could not be obtained because none of the patients who retained the allograft had died by the time the study was conducted.
Deceased donor is the reference group.