Table 3.

Association Between Insulin-Like Growth Factor- 1 (IGF-1) and IGF-1 Binding Proteins (IGFBPs) and Mortality

Outcome Variable	Basic Adjustment*	Full Adjustment†
	Hazard Ratio (95% Confidence Interval) P-Value
	IGF-1/SD	1.05 (0.88–1.27) .58	1.12 (0.91–1.37) .29
IGFBP-1/SD	1.28 (1.06–1.56) .01	1.34 (1.01–1.76) .04
IGFBP-2/SD	1.52 (1.27–1.82) <.001	1.48 (1.14–1.92) .003

^*Adjusted for race, sex, study site, and baseline age.

^†Adjusted for race, sex, study site, baseline age height, weight, visceral fat, total percent fat, fasting glucose, fasting insulin, serum interleukin 6, and serum C-reactive protein. IGF-1, IGFBP-1, and IGFBP-2 were log transformed.

SD = standard deviation.