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. Author manuscript; available in PMC: 2009 Nov 2.
Published in final edited form as: Neuropsychopharmacology. 2006 Oct 25;32(2):471–482. doi: 10.1038/sj.npp.1301234

Table 2.

Characteristics of Individual Subjects

MDD Age (years)/
gender/race		 PMI pH Cause
of death		 Medicationa Toxicology Drugs/
alcohb 		Comorbid
diagnosis		 Family
history		 Duration of
illness (years)c 		Hospitald Smoker
1 34/F/C 27.0 6.27 S Trazodone, ALPRAZOLAM, risperidone, AMOXICILLIN, VALPROIC ACID, NITROFURINTOIN CO, EtOH-blood, alprazolam None None NA 20 Several No
2 30/M/AAm 18.0 6.91 S NA EtOH-blood Hx AA Borderline personality disorder AD, MD, S, SA 3 3 Yes
3 40/F/C 25.0 6.32 N+Ac TEMAZEPAM, FLUOXETINE, HYDROCODONE, etodolac Morphine, codeine, hydrocodone, diphenhydramine DA None AD, DA 5 0 No
4 42/F/C 24.0 6.62 S FLUOXETINE, AMITRIP, PAROXETINE, PROPOXY, DIAZEPAM, FUROSEMIDE Propoxyphene, acetaminophen PS, DA Bulimia nervosa AD 26 2 No
5 42/M/C 20.0 6.64 S SERTRALINE Sertraline, diphenhydramine None None MD, SA 0.25 0 No
6 46/M/AAm 17.0 6.26 H None Clean NA None SA 1 0 No
7 54/M/C 23.0 6.24 Ac SERTRALINE CO, phenobarbital, phenytoin None None AD 3 6 Hx
8 63/F/C 24.0 6.32 N CHLORPROMAZINE, CLONAZEPAM, AMITRIP, AMANTIDINE Amitrip., chlorpromazine, amantadine, lidocaine PS, DA, AD AD, I 30 8 Yes
9 73/M/C 10.0 6.57 S NORTRIPTYLINE Nortriptyline None OCPD None 5 0 Yes
10 73/F/C 17.0 6.57 N Lithium carbonate, NORTRIP, restoril, CLONAZEPAM, levothyroxine Clean Hx AD Panic attacks AD, MD, SA 50 35 Yes
11 86/M/C 21.0 6.23 S FLUOXETINE, ATENOLOL, leuprolide acetate Clean None None S 20 3 Quit in 1929
12 74/M/C 25.0 6.67 S Chlorpromazine, trazodone, clorazepate, methylphenidate, pentazocine, quinapril, diphenoxylate, hydrosine, dyazide, captopril, alupent, betamethazone, prednisone Diazepam, acetominophen None None AA 24 1
13 78/F/C 25.0 6.94 S Lorazepam Clean NA Pathological gambling None 5 0 No
14 45/M/C 29.0 6.86 S Methylphenidate EtOH 0.11 blood AA, DA AA, PS 7 0 Hx
CNTL Age (years)/gender/race PMI pH Cause of death Medication Toxicology Drugs/alcohb Comorbid diagnosis Family history Duration of illness (years) Hospitald Smoker
1 24/M/AAm 15.0 6.84 H None Clean None AD No
2 27/F/C 15.0 7.01 N Enalapril, metoprolol, captopril, lopressor Clean None None No
3 30/F/C 9.0 6.75 N None Clean NA NA NA
4 47/M/C 17.0 6.89 N None Clean None AA Yes
5 71/M/C 24.0 6.82 N None Clean ADe AA Yes
6 42/M/C 20.0 6.82 N None Clean None MDD Hx
7 50/F/C 27.0 6.74 N None Clean None None Yes
8 51/M/C 28.0 6.64 N None Clean None AD, MDD, SA Yes
9 52/M/C 17.0 6.87 N Cholesterol-lowering drug Clean None None No
10 69/M/C 18.0 6.70 N None Clean None AA, MDD No
11 77/M/C 24.0 6.56 N Glyburide, maxide, atenolol Clean None DA No

AA = alcohol abuse; AAm = African American; Ac = accident; AD = alcohol dependence; Amitrip. = amitriptyline; C = Caucasian; CNTL = control; DA = drug abuse; EtOH = ethanol; H = homicide; Hx = history; I = institutionalized; MDD = major depressive disorder; N = natural; NA = not available; Nortrip = nortripyline; OCPD = obsessive compulsive personality disorder; PD = polysubstance dependence; PMI = post-mortem interval (h); defined as the time between the time of death and the beginning of the formalin-fixation process; PS = polysubstance abuse; S = suicide; SA = suicide attempt; TF = time in formalin (months).

a

Capitalized drugs were prescribed in last month of life.

b

Defined as psychoactive substance use disorder.

c

The duration of illness covers the time between the first display (and not necessarily diagnosis) of symptoms of a depressive illness and the time of death.

d

The number of recorded hospitalizations related to depression.

e

History of alcohol dependence 32 years before death.