Table 2.

Estimation of the statistical significance of the difference between the FROC curves for three approaches: The single CAD system, the dual system, and the two-view dual system. The FROC curves with the FP marker rates obtained from the normal data set were compared. The pairs of image-based FROC curves were compared to JAFROC methodology. The figure of merit from JAFROC analysis for each curve is shown.

JAFROC Analysis	FOM (subtle masses)
	All cases		Malignant cases
	Test subset 1	Test subset 2	Test subset 1	Test subset 2
Single system	0.42	0.39	0.37	0.32
Dual system	0.48	0.46	0.48	0.45
p values	<0.0001	<0.0001	<0.0001	<0.0001
Dual system	0.48	0.46	0.48	0.45
Two-view dual system	0.52	0.49	0.52	0.48
p values	0.111	0.078	0.305	0.219
Single system	0.42	0.39	0.37	0.32
Two-view dual system	0.52	0.49	0.52	0.48
p values	<0.0001	<0.0001	<0.0001	<0.0001