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. 2009 Nov 2;106(46):19280–19285. doi: 10.1073/pnas.0905470106

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Fig. 8. — Synthetic neolactotetra glycoclusters inhibit attachment of neolactotetra-bearing Neisseria to immobilized Borrelia. Structures of glycoclusters bearing 3, 4, 6, 12, or 18 neolactotetra moieties synthesized on a carbosilane core (A). Attachment of Neisseria to Borrelia can be inhibited by glycoclusters bearing 12 or 18 but not 3, 4, or 6 neolactotetra moieties (B). Attachment of Neisseria to Borrelia is completely inhibited by Dumbbell (2)18 and N. meningitidis LOS mutant ΔlpxA (C). Standard deviations are shown. **, P <0.01.