Table 2.
Gene Ontology (GO) categories, with names and identification numbers, displaying significant over-representation of genes, and the respective gene names and their symbols
| GO Category/GOBPID | Genes | Symbol |
|---|---|---|
| blood vessel development/GO:0001568 | angiopoietin-like 4 | Angptl4 |
| B-cell translocation gene 1, anti-proliferative | Btg1 | |
| connective tissue growth factor | Ctgf | |
| endothelial-specific receptor tyrosine kinase | Tek | |
| forkhead box O1A | Foxo1a | |
| gap junction membrane channel protein alpha 1 | Gja1 | |
| neurotrophic tyrosine kinase, receptor, type 2 | Ntrk2 | |
| phosphatidic acid phosphatase type 2B | Ppap2b | |
| protein O-fucosyltransferase 1 | Pofut1 | |
| secretogranin 2 | Scg2 | |
| small inducible cytokine subfamily E, member 1 | Scye1 | |
| transforming growth factor alpha | Tgfa | |
| tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | Tie1 | |
| regionalization/GO:0003002 | activity regulated cytoskeleton-associated protein | Arc |
| B-cell translocation gene 2, anti-proliferative | Btg2 | |
| E1A binding protein p300 | Ep300 | |
| Huntington disease gene homolog | Hdh | |
| lymphoid enhancer binding factor 1 | Lef1 | |
| protein O-fucosyltransferase 1 | Pofut1 | |
| ring finger protein 2 | Rnf2 | |
| negative regulation of protein kinase activity/GO:0006469 | caveolin | Cav |
| dual specificity phosphatase 6 | Dusp6 | |
| protein kinase inhibitor beta, cAMP dependent, catalytic | Pkib | |
| regulator of G-protein signalling 3 | Rgs3 | |
| sprouty homolog 2 | Spry2 | |
| isoprenoid metabolic process/GO:0006720 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Hmgcr |
| dehydrogenase/reductase (SDR family) member 3 | Dhrs3 | |
| isopentenyl-diphosphate delta isomerase notch1-induced protein phytn-dehydro and Pyr-redox domain containing protein | Idi1 | |
| one-carbon compound metabolic process/GO:0006730 | B-cell translocation gene 1, anti-proliferative | Btg1 |
| carbonic anhydrase 11 | Car11 | |
| FBJ murine osteosarcoma viral oncogene homolog | Fos | |
| isoprenylcysteine carboxyl methyltransferase | Icmt | |
| methionine adenosyltransferase II, alpha | Mat2a | |
| methyl-CpG binding domain protein 1 | Mbd1 | |
| protein tyrosine phosphatase, receptor type, G | Ptprg | |
| anti-apoptosis/GO:0006916 | a disintegrin and metalloproteinase domain 17 | Adam17 |
| FGF receptor activating protein 1 | Frag1 | |
| Forkhead box O1A | Foxo1a | |
| heat shock 70kDa protein 5 (glucose-regulated protein) | Hspa5 | |
| hormone-regulated proliferation associated protein 20 | Hrpap20 | |
| Huntington disease gene homolog | Hdh | |
| superoxide dismutase 2, mitochondrial | Sod2 | |
| transforming growth factor alpha | Tgfa | |
| TSC22 domain family 3 | Tsc22d3 | |
| zinc finger protein 91 | Zfp91 | |
| microtubule-based movement/GO:0007018 | actin-related protein 10 homolog | Actr10 |
| Huntington disease gene homolog | Hdh | |
| kinesin family member 1B | Kif1b | |
| kinesin family member 6 | Kif6 | |
| kinesin family member 11 | Kif11 | |
| kinesin heavy chain family, member 2 | Kif2 | |
| kinesin light chain 1 | Klc1 | |
| tubulin, beta 2b | Tubb2b | |
| gamete generation/GO:0007276 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Hmgcr |
| a disintegrin-like and metallopeptidse with thrombospondin type 1 motif, 1 | Adamts1 | |
| B-cell translocation gene 1, anti-proliferative | Btg1 | |
| carnitine deficiency-associated gene expressed in ventricle 1 | Cdv1 | |
| dead end homolog 1 | Dnd1 | |
| heat shock factor 2 | Hsf2 | |
| hydroxyacyl glutathione hydrolase | Hagh | |
| kinesin family member 6 | Kif6 | |
| McKusick-Kaufman syndrome protein | Mkks | |
| nitric oxide synthase 3, endothelial cell | Nos3 | |
| seven in absentia 1A | Siah1a | |
| zinc finger protein 403 | Zfp403 | |
| gastrulation/GO:0007369 | camello-like 3 | Cml3 |
| Huntington disease gene homolog | Hdh | |
| nuclear receptor subfamily 4, group A, member 3 | Nr4a3 | |
| phosphatidic acid phosphatase type 2B | Ppap2b | |
| ring finger protein 2 | Rnf2 | |
| heart development/GO:0007507 | E1A binding protein p300 | Ep300 |
| endothelial-specific receptor tyrosine kinase | Tek | |
| gap junction membrane channel protein alpha 1 | Gja1 | |
| histone deacetylase 5 | Hdac5 | |
| McKusick-Kaufman syndrome protein | Mkks | |
| plakophilin 2 | Pkp2 | |
| protein O-fucosyltransferase 1 | Pofut1 | |
| transforming growth factor, beta receptor 3 | Tgfbr3 | |
| regulation of G-protein coupled receptor protein signaling/GO:0008277 | endothelin converting enzyme 1 | Ece1 |
| phospholipase C, epsilon 1 | Plce1 | |
| RAS guanyl releasing protein 4 | Rasgrp4 | |
| receptor (calcitonin) activity modifying protein 2 | Ramp2 | |
| regulator of G-protein signaling 3 | Rgs3 | |
| regulator of G-protein signaling 9 | Rgs9 | |
| protein catabolic process/GO:0030163 | calpastatin | Cast |
| gap junction membrane channel protein alpha 1 | Gja1 | |
| prenylcysteine oxidase 1 | Pcyox1 | |
| proteasome (prosome, macropain) 26S subunit, ATPase, 6 | Psmc6 | |
| proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | Psmd12 | |
| proteasome (prosome, macropain) subunit, alpha type 4 | Psma4 | |
| seven in absentia 1A | Siah1a | |
| seven in absentia 2 | Siah2 | |
| ubiquitin associated domain containing 1 | Ubadc1 | |
| ubiquitin carboxyl-terminal hydrolase L5 | Uchl5 | |
| ubiquitin-conjugating enzyme E2D 3 | Ube2d3 | |
| protein modification by small protein conjugation/GO:0032446 | calcyclin binding protein | Cacybp |
| LIM domain only protein 7 | Lmo7 | |
| retinoblastoma binding protein 6 | Rbbp6 | |
| ring finger protein 2 | Rnf2 | |
| seven in absentia 1A | Siah1a | |
| seven in absentia 2 | Siah2 | |
| ubiquitin associated domain containing 1 | Ubadc1 | |
| negative regulation of programmed cell death/GO:0043069 | a disintegrin and metalloproteinase domain 17 | Adam17 |
| angiopoietin-like 4 | Angptl4 | |
| B-cell translocation gene 2, anti-proliferative | Btg2 | |
| FGF receptor activating protein 1 | Frag1 | |
| Forkhead box O1A | Foxo1a | |
| heat shock 70kDa protein 5 (glucose-regulated protein) | Hspa5 | |
| hormone-regulated proliferation associated protein 20 | Hrpap20 | |
| Huntington disease gene homolog | Hdh | |
| secretogranin 2 | Scg2 | |
| superoxide dismutase 2, mitochondrial | Sod2 | |
| transforming growth factor alpha | Tgfa | |
| TSC22 domain family 3 | Tsc22d3 | |
| zinc finger protein 91 | Zfp91 | |
| regulation of MAPK activity/GO:0043405 | caveolin | Cav |
| cholinergic receptor, nicotinic, alpha polypeptide 7 | Chrna7 | |
| dual specificity phosphatase 6 | Dusp6 | |
| phospholipase C, epsilon 1 | Plce1 | |
| regulator of G-protein signaling 3 | Rgs3 | |
| sprouty homolog 2 | Spry2 | |
| transforming growth factor alpha | Tgfa | |
| biopolymer methylation/GO:0043414 | B-cell translocation gene 1, anti-proliferative | Btg1 |
| B-cell translocation gene 2, anti-proliferative | Btg2 | |
| FBJ murine osteosarcoma viral oncogene homolog | Fos | |
| isoprenylcysteine carboxyl methyltransferase | Icmt | |
| methyl-CpG binding domain protein 1 | Mbd1 | |
| regulation of kinase activity/GO:0043549 | caveolin | Cav |
| cell division cycle 42 homolog | Cdc42 | |
| cholinergic receptor, nicotinic, alpha polypeptide 7 | Chrna7 | |
| diacylglycerol kinase, alpha | Dgka | |
| dual specificity phosphatase 6 | Dusp6 | |
| phospholipase C, epsilon 1 | Plce1 | |
| protein kinase inhibitor beta, cAMP dependent, catalytic | Pkib | |
| regulator of G-protein signaling 3 | Rgs3 | |
| speedy homolog 1 | Spdy1 | |
| sprouty homolog 2 | Spry2 | |
| transforming growth factor alpha | Tgfa | |
| cell maturation/GO:0048469 | actin, alpha 1, skeletal muscle | Acta1 |
| calpastatin | Cast | |
| gap junction membrane channel protein alpha 1 | Gja1 | |
| growth differentiation factor 11 | Gdf11 | |
| hairy and enhancer of split 1 | Hes1 | |
| parathyroid hormone receptor 1 | Pthr1 | |
| anatomical structure formation/GO:0051603 | angiopoietin-like 4 | Angptl4 |
| B-cell translocation gene 1, anti-proliferative | Btg1 | |
| connective tissue growth factor | Ctgf | |
| endothelial-specific receptor tyrosine kinase | Tek | |
| Huntington disease gene homolog | Hdh | |
| nuclear receptor subfamily 4, group A, member 3 | Nr4a3 | |
| protein O-fucosyltransferase 1 | Pofut1 | |
| secretogranin 2 | Scg2 | |
| small inducible cytokine subfamily E, member 1 | Scye1 | |
| transforming growth factor alpha | Tgfa | |
| tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | Tie1 |