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. Author manuscript; available in PMC: 2009 Nov 3.
Published in final edited form as: Open Neurosci J. 2009 Jan 1;3:40–47. doi: 10.2174/1874082000903010040

Fig. (4). Effect of Hypoxia and Hypoglycemia on Temperature-Induced Current Responses of Cultured Cortical Astrocytes.

Fig. (4)

A. Responses of a control astrocyte and B. an astrocyte subjected to simulated ischemia (24 hrs anoxia at reduced glucose (1/10 normal, 2.5 mM)) to a ramp and step protocol at 24°C and 34°C, in the presence of other K+ channel blockers (Ba 0.1 mM, TEA 6mM, 4-AP 4mM, tolbutamide 0.5 mM). [K]o = 3 mM. C: Summary of % increase in outward current with increased temperature, (max current at 34°C over max current at 24°C × 100) of control astrocytes and astrocytes exposed to experimental ischemia. The asterisk indicates a significant difference from control (t-test; p<0.05). (n=5 for each group).