. Author manuscript; available in PMC: 2010 Apr 17.

Published in final edited form as: Cell. 2009 Apr 17;137(2):321–331. doi: 10.1016/j.cell.2009.02.041

Table 1. Glycoproteins of B. fragilis.

Gene	Size (aa)	Signal^a	Subcellular Location	Sequence Features
BF0447	169	I	Periplasm	Similar to E. coli chaperone Skp
BF0522	210	II	Outer Membrane - Facing Surface	-
BF0935	939	I	Periplasm	Zinc endopeptidase (M16 family)
BF0994	712	I	Periplasm	Proline cis-trans isomerase (parvulin family)
BF2334	245	I	Periplasm	TPR domains (residues 59-92 and 134-167)
BF2494	403^b	I^b	Periplasm	TPR domains (residues 181-350)
BF3567	623	II	Outer Membrane - Facing Surface	-
BF3918	677	II	Outer Membrane - Facing Periplasm	Zinc endopeptidase (M13 family)

Type of signal peptidase cleavage site predicted by LipoP (Juncker et al., 2003).

Translation of this protein appears to begin 7 codons upstream of the start codon indicated by the genome annotation, making the protein 403 residues in length rather than 396. The longer sequence, unlike the shorter one, is predicted to have a signal peptide by LipoP, consistent with our experimental evidence showing that the protein is located in the periplasm.