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Attenuated bmh1 mutants induce an altered cytokine response in vivo. Organs were removed from mice infected with Candida control and bmh1 mutant strains 48 h p.i. Expression of TNF-α was determined by QRT-PCR from kidney (a) and spleen (b). Gene expression was normalized against GAPDH expression levels, and the results expressed as fold induction compared with untreated controls. *Significantly different (P<0.05) from WT and BMH. All samples were analysed in triplicate.
