Skip to main content
. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Exp Hematol. 2009 Aug 28;37(11):1295–1309. doi: 10.1016/j.exphem.2009.08.005

Figure 1.

Figure 1

B cells from primary Non-Hodgkin Lymphomas express TrkA. (A) A panel of single cell suspensions derived from patient biopsies of NHL were adhered to glass slides via cytospin. Immunofluorescence was performed using antibodies specific for CD19 (to identify B cells) and surface TrkA. Each patient’s cells expressed similar levels of TrkA on the surface of B cells derived from NHL tumors (TrkA: green, CD19: red and DAPI: blue). (B) DLBCL cell lines express Trk. The DLBCL cell lines were analyzed via immunoblot for expression of Trk receptors using a pan-Trk antibody, which recognizes TrkA, TrkB and TrkC. As shown, all cell lines exhibit pan-Trk expression. (C) The specific Trk receptors expressed was determined by RT-PCR in OCI-LY3 and OCI-LY19.