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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Exp Hematol. 2009 Aug 28;37(11):1295–1309. doi: 10.1016/j.exphem.2009.08.005

Figure 8.

Figure 8

K252a treatment results in inhibition of NF-κB transcriptional activity and IL-6 production in OCI-LY3. (A) NF-κB transcriptional activity was analyzed in a luciferase assay of K252a treated OCI-LY3. Exposure of these cells to K252a leads to an inhibition of NF-κB-dependent transcriptional activity. Results are mean +/- SEM of 3 observations. ### equals p<0.001. (B) K252a treatment inhibits IL-6 production in OCI-LY3. Cells were treated with 100nM K252a for 24h followed by ELISA analysis of supernatants for IL-6. Results are mean +/- SEM of 3 observations. # equals p<0.05.