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. Author manuscript; available in PMC: 2010 Aug 27.
Published in final edited form as: Vaccine. 2009 Jul 17;27(39):5299–5306. doi: 10.1016/j.vaccine.2009.06.101

Figure 3. Cytokine/chemokine mRNA expression in the lungs of vaccinated mice is rapidly up-regulated following i.t. challenge with F. tularensis LVS.

Figure 3

Groups of control (solid bar) and vaccinated (open bar) mice were infected i.t. with 6 LD50 F. tularensis LVS. The lungs were dissected at 4 hours and 3 days post-infection; cytokine and chemokine mRNA expression was quantified by real-time RT-PCR. Data are the means ± SD derived from 4 mice treated comparably. A second experiment yielded similar results. *Vaccinated group is significantly different from control: P<0.05.