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. Author manuscript; available in PMC: 2010 Aug 27.
Published in final edited form as: Vaccine. 2009 Jul 17;27(39):5299–5306. doi: 10.1016/j.vaccine.2009.06.101

Table 3.

The bacterial burden of the lungs is decreased in vaccinated micea

Tissue CFUs/mg tissue
pVAX1 control Vaccine construct
Lungs 27,352 ± 10,251 13,561 ± 1,428b
Liver 53 ± 16 66 ± 55
Spleen 13 ± 5 17 ± 9
a

Groups (n=4) of control and vaccinated mice were challenged i.t. with 2 LD50 F. tularensis LVS. Values are the mean colony forming units ± SD/mg tissue dissected on day 3 postinfection.

b

Significantly less than pVAX1 control; P=0.029 (Mann-Whitney Rank Sum Test).