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PK studies. Free serum concentrations (conc) of plectasin in mice after s.c. treatment with doses from 4.25 to 34 mg/kg are shown to illustrate the fT>MIC and fAUC for the different dosing regimens. The MIC against S. aureus E33235 was 2 mg/liter. The lowest dose level did not reach serum concentrations above the MIC (see Table 2).
