TABLE 2.
Comparison of HCMV force of infection, basic reproductive rates, and average ages of infection in different countries
| Location (yr studied)a | Population | Force of infectionb (95% CI) | Basic reproductive rate (95% CI) | Average age (yr) of infection (95% CI) | Reference |
|---|---|---|---|---|---|
| Shanghai, China (2006-2008) | Entire Shanghai population | 8.04 (6.36-9.72) | 5.65 (4.50-6.81) | 7.87 (7.19-8.68) | |
| Australia (2002) | Entire Australia population | 1.89 (1.53-2.26) | 1.80 (1.63-1.99) | 27.50 (26.14-28.87) | 19 |
| São Paulo, Brazil (1990-1991) | Entire São Paulo population | Age dependentc | 5.02 mo, 19.84 yr | 3 | |
| ARM, Spain (1993) | Entire ARM population | 4.98 (2.91-7.05) | 3.60 (2.34-4.97) | 17.87 (13.68-23.87) | 7 |
| ARM, Spain (1999) | Entire ARM population | 3.37 (2.63-4.11) | 2.61 (2.19-3.05) | 22.37 (20.15-24.82) | 7 |
| London, UK (1975-1982) | Pregnant women | 3.10 | 2.40 | 32.00 | 10 |
| London, UK (1983-1985) | Pregnant women | 3.50 | 2.70 | 29.00 | 10 |
| United States (1988-1994) | Entire U.S. population | 1.60 (1.30-1.90) | 1.70 (1.50-1.80) | 28.60 (27.30-29.40) | 6 |
a
ARM, Autonomous Region of Madrid; UK, United Kingdom.
b
No. of individuals infected by HCMV per 100 susceptible individuals per year.
c
The age-dependent force of infection has its highest value early in childhood and then drops quickly to nearly 5 years of age. Afterward, it increases slowly (from 5 to 15 years old) and then decreases again at a minimum speed during the life span (3).