TABLE 1.
Spirochete | Growth medium | Expt I |
Expt II |
Expt III |
Total no. of mice (n = 142 [7]) | |||
---|---|---|---|---|---|---|---|---|
Dose (CFU)/mouse | No. of mice (n = 48 [0]) | Dose (CFU)/mouse | No. of mice (n = 36 [2]) | Dose (CFU)/mouse | No. of mice (n = 58 [5]) | |||
B. burgdorferi sensu stricto N40 | BSK-II | 106 | 6 | 106 | 10 | 106 | 5 | 21 |
B. garinii PBi | BSK-II | 106 | 6 | 106 | 10 | 6.0 × 105 | 5 | 21 |
B. afzelii PKo | MKP | 106 | 6 | - | 0 | 106 | 17 | 23 |
B. afzelii Slovakia | BSK-II | 106 | 6 | - | 0 | 7.6 × 105 | 15 | 21 |
B. valaisiana VS116 | BSK-II | 106 | 6 | - | 0 | - | 0 | 6 |
B. valaisiana Rio6 | BSK-II | - | 0 | 106 | 8 | - | 0 | 8 |
B. spielmanii A14S | BSK-II | 106 | 12 | - | 0 | 106 | 6 | 18 |
B. lusitaniae | BSK-II | 106 | 6 | 106 | 8 | 106 | 10 | 24 |
For experiments I and III, the collection of murine serum samples occurred on days 28, 56, and 63 postinoculation, and mice were sacrificed on day 63. For experiment II, the collection of murine serum samples occurred on days 28, 56, and 84 postinoculation, and mice were sacrificed on day 90. n, Total number of mice (values in brackets indicate the number of negative-control mice). -, No inoculation with this spirochete.