FIG. 2.
Statistical selection of immunogenic antigens. In a display of the results of the significance test of log10-transformed screening data, eight proteins (black) show signal changes between the CBPP-positive and CBPP-negative populations that are >3 and statistically significant, with P values ranging from 10−6 to 10−18. Additionally, four proteins (gray) displayed changes with significance exceeding the P value limit of 0.01, but with less discriminative importance than the top eight. Based on this test, the top eight proteins were selected as candidates for an antigen cocktail ELISA.